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1.
National Journal of Andrology ; (12): 545-550, 2009.
Article in Chinese | WPRIM | ID: wpr-241302

ABSTRACT

<p><b>OBJECTIVE</b>To evaluate the association between vasectomy and prostate cancer.</p><p><b>METHODS</b>We searched comprehensively the databases, CBMDisc, CMCC, CMAC, CNKI (from 1978 to January 6, 2009), and PubMed (from 1965 to January 6, 2009) using the key words "vasectomy" and "prostate cancer", screened the retrieved literature according to the inclusion and exclusion criteria, performed a Meta-analysis with the software RevMan 4.2 after identification of the relevant data, and calculated the overall pooled OR (95% CI) as well as that of the association of prostate cancer with <20 and > or =20 yr vasectomy.</p><p><b>RESULTS</b>A total of 20 088 cases and 232 506 controls in 27 reports (7 cohort and 20 case-control studies) were included in this investigation. The overall pooled OR (95% CI) was 1.10 (0.97-1.24), and those of <20 and > or =20 yr vasectomy were 0.94 (0.83-1.06) and 1.05 (0.90-1.23), respectively.</p><p><b>CONCLUSION</b>No existing literature show any positive association between vasectomy and prostate cancer.</p>


Subject(s)
Humans , Male , Prostatic Neoplasms , Epidemiology , Risk Factors , Vasectomy
2.
National Journal of Andrology ; (12): 618-623, 2008.
Article in Chinese | WPRIM | ID: wpr-309824

ABSTRACT

<p><b>OBJECTIVE</b>To investigate the correlation between Ureaplasma urealyticum infection and infertility in Chinese males.</p><p><b>METHODS</b>According to the results of the heterogeneity test, a comprehensive quantitative analysis was made of 49 papers on Ureaplasma urealyticum infection and Chinese male infertility by RevMan 4.2.2. The impacts of different sample volumes on the research findings were compared, and the sensitivities of culture and PCR detections analyzed respectively.</p><p><b>RESULTS</b>Ureaplasma urealyticum had a significant negative impact on Chinese male fertility. Based on different samples of literature, two rounds of screening and analysis were carried out and two different conclusions derived. The first was OR = 4.43 (95% CI: 3.77-5.22), with the OR values of culture and PCR detections as 4.25 (95% CI: 3.59-5.03) and 5.35 (95% CI: 3.37-8.47), and the second was OR = 4.28 (95% CI: 3.52-5.20), with the OR values of culture and PCR detections as 4.24 (95% CI: 3.41-5.28) and 4.42 (95% CI: 2.73-7.17).</p><p><b>CONCLUSION</b>There is a significant correlation between Ureaplasma urealyticum and Chinese male infertility. The conclusion of study is significantly influenced by the sample volume, which should be reasonably designed. The sensitivity of PCR detection is higher than that of culture detection.</p>


Subject(s)
Humans , Male , China , Epidemiology , Infertility, Male , Epidemiology , Polymerase Chain Reaction , Ureaplasma Infections , Epidemiology , Microbiology , Ureaplasma urealyticum , Genetics
3.
National Journal of Andrology ; (12): 704-708, 2008.
Article in Chinese | WPRIM | ID: wpr-309810

ABSTRACT

<p><b>OBJECTIVE</b>To investigate the relationship of seminal plasma levocarnitine with sperm concentration, vitality and motility.</p><p><b>METHODS</b>Enrolled in this study were 64 infertile men, who were divided according to the results of routine sperm tests into a normozoospermia (n = 12), an oligozoospermia (n = 16), an asthenozoospermia (n = 20) and an oligoasthenozoospermia group (n = 16). The level of seminal plasma levocarnitine was detected by LC-MS-MS, the concentration of seminal plasma testosterone measured by chemiluminescence immunoassay, the correlation of seminal plasma levocarnitine with sperm concentration, motility and vitality determined by bivariate correlation analysis with SPSS15.0, and so was the correlation between the carnitine and sperm concentration by partial correlation analysis with seminal plasma testosterone as a control variable to exclude the influence of testosterone.</p><p><b>RESULTS</b>The concentrations of total seminal plasma levocarnitine, free seminal plasma levocarnitine and seminal plasma acetolevocarnitine were (91.33 +/- 40.49) mg/L, (40.89 +/- 24.13) mg/L and (50.44 +/- 21.90) mg/L; the Pearson coefficients of correlation of the levocarnitine level with sperm motility, vitality and concentration were 0.161 (P = 0.235), 0.114 (P = 0.370) and 0.637 (P < 0.001), those of free seminal carnitine with sperm motility and vitality were 0.325 (P = 0.024) and 0.316 (P = 0.029), respectively, with the oligozoospermia group excluded, and that of partial correlation between the concentrations of seminal levocarnitine and sperm was 0.641 (P < 0.001).</p><p><b>CONCLUSION</b>The level of seminal plasma levocarnitine is positively correlated with sperm motility and vitality, and more significantly with sperm concentration.</p>


Subject(s)
Adult , Humans , Male , Young Adult , Carnitine , Infertility, Male , Semen , Chemistry , Cell Biology , Sperm Count , Sperm Motility , Physiology , Spermatozoa , Cell Biology , Physiology
4.
Journal of Third Military Medical University ; (24): 522-523, 2001.
Article in Chinese | WPRIM | ID: wpr-737021

ABSTRACT

Objective Coronary artery bypass grafting (CABG)i n 13 patients was analyzed. Methods 9 patients were performed C ABG with cardiopulmonary bypass, 4 patients undergone off-pump coronary artery bypass(OPCAB). Among the 4 patients, 3 undergone transmyocardial laser revascula rization concomitantly. 2 patients with single-vessel disease, 3 with double-v essel disease, 7 with triple-vessel disease and 1 with left main coronary arter y disease. The average bypass per patient was 2.3. Results All patients survived, 11 patients were angina free, 2 were angina relief. C onclusion CABG is a safe operation, OPCAB may reduce blood transfusion and complication, patients recover more quickly after OPCAB compared with those with CABG.

5.
Journal of Third Military Medical University ; (24): 522-523, 2001.
Article in Chinese | WPRIM | ID: wpr-735553

ABSTRACT

Objective Coronary artery bypass grafting (CABG)i n 13 patients was analyzed. Methods 9 patients were performed C ABG with cardiopulmonary bypass, 4 patients undergone off-pump coronary artery bypass(OPCAB). Among the 4 patients, 3 undergone transmyocardial laser revascula rization concomitantly. 2 patients with single-vessel disease, 3 with double-v essel disease, 7 with triple-vessel disease and 1 with left main coronary arter y disease. The average bypass per patient was 2.3. Results All patients survived, 11 patients were angina free, 2 were angina relief. C onclusion CABG is a safe operation, OPCAB may reduce blood transfusion and complication, patients recover more quickly after OPCAB compared with those with CABG.

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